Green Propolis Better than Red in Helping to Heal Wounds

To contact us Click HERE

Comparative Study of Topical Green and Red Propolis in the Repairof Wounds Induced in Rats
Rev Col Bras Cir, 2012 Dec;39(6):515-520OBJECTIVE:To evaluate the healing action of green and red propolis,correlating it with the content of flavonoids.METHODS: We performed quantification of total flavonoids of green andred propolis ethanol extracts for subsequent incorporation in ointment base to20%. We used 20 Wistar rats divided into four groups: 0.9% saline (S), ointmentbase (B), green propolis ointment (G) and red propolis ointment (R). Allanimals were submitted to excisional lesions in the midian back region. Therats were treated daily for 15 days. During this period we observed weight,body temperature and diameters of the wounds. For histological analysis,samples were collected from wounds. At the end of the experiment we performedblood collection and removal of the kidney and liver for biochemical andhistological analyzes.RESULTS: The levels of total flavonoids of green (4.50%) and red(5.92%) propolis were high (> 2%), but, while the latter showed a contentlarger than the former, the evolution of green propolis was better in therepair of wounds, both macroscopically and histologically. There were nonephrotoxicity or hepatotoxicity, a result confirmed by biochemical tests (ALTand albumin). Propolis influenced the reduction of total cholesterol,triglycerides and glucose.CONCLUSION: There was no correlation between total flavonoid contentsand the healing action of propolis. This reveals the need for elucidation ofthe flavonoids found in each class of propolis to unravel which one(s) would beimportant for the healing process.