Manuka Honey Boosts Healing of Horse Wounds

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The Effect of Short- and Long-Term Treatment with ManukaHoney on Second Intention Healing of Contaminated and Noncontaminated Wounds onthe Distal Aspect of the Forelimbs in HorsesVeterinary Surgery, 5 DEC 2012 MethodsFive full-thickness wounds (2 × 2 cm) were created on bothmetacarpi. Wounds on 1 forelimb were covered with horse feces for 24 hours.Wounds on the contralateral limb were left uncontaminated. Wounds were assignedto the following 5 different treatments: manuka honey, manuka honey gel or gelapplied for 12 days, manuka honey gel applied throughout healing and untreatedcontrol. Wound area was measured on day 1 then weekly until day 42 and time tocomplete healing was recorded. ResultsWounds treated with manuka honey gel throughout healinghealed faster than all other wounds (P < .05). Wounds treated with manukahoney and manuka honey gel for 12 days healed faster than gel control anduntreated control wounds (P < .05). Wounds treated with manuka honey andmanuka honey gel for 12 days and throughout healing were smaller than gelcontrol and untreated control wounds until day 35 (P < .05). Woundscontaminated with feces had greater retraction for 7 days, but healed fasterthan noncontaminated wounds (P < .05). ConclusionsTreatment of wounds with manuka honey and manuka honey gelreduced wound retraction and overall healing time compared with gel anduntreated control wounds.